Phaeochromocytoma with Normal Urinary Catecholamines: The Potential Value of Urinary Free Metadrenalines

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Factors influencing the urinary excretion of free catecholamines in man.

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Determination of Total Urinary Catecholamines

SYNOPSIS Two patients with phaeochromocytoma having atypical biochemical features are described. Total catecholamine excretion was normal in one and only slightly raised in the other; both had a diagnostic rise in output of metadrenaline and 4-hydroxy-3-methoxymandelic acid whilst 4-hydroxy-3-methoxyphenylglycol excretion was increased in one of them. During hypertensive attacks adrenaline excr...

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Biochemical detection of phaeochromocytoma: should we still be measuring urinary HMMA?

AIMS To compare the diagnostic value of biochemical tests in the detection of phaeochromocytoma. METHODS Urinary catecholamines and metabolites were measured by high performance liquid chromatography in the initial 24 hour collections from 31 patients with histologically confirmed phaeochromocytoma. Results were compared with values from 50 patients investigated for the possible presence of a...

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Urinary and plasma catecholamines and urinary catecholamine metabolites in pheochromocytoma: diagnostic value in 19 cases.

We review our data on the measurement of catecholamines and their metabolites in 19 patients with pheochromocytoma. All the assays were specific high-performance liquid chromatographic procedures with electrochemical detection. The assay of fractionated metanephrines was 100% sensitive. Normal values for both urinary norepinephrine and epinephrine were found in two asymptomatic patients with ph...

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ژورنال

عنوان ژورنال: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

سال: 2002

ISSN: 0004-5632,1758-1001

DOI: 10.1177/000456320203900603